Flp Lines
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Please list your new Flp line here. This will help our community members learn more about the new Flp line and where it is available.
Repositories
- Jackson: The Jackson Laboratory
- RBRC: Riken BioResource Research Center
- MMRRC: Mutant Mouse Resource & Research Centers
- CARD: Center for Animal Resources and Development
- EMMA: The European Mouse Mutant Archive
For questions mail to: kpyo@stanford.edu
Driver | Full Gene Name | Flp protein format | Construction Approach | Species | Author | Journal | Year published | PMID | MGI | Repository/Vendor | Repository/Vendor product ID | Article link |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Actb | actin beta | FlpE | Random integration | Mouse | Rodriguez | Nature Genetics | 2000 | 10835623 | 2448985 | Jackson | 3800 | https://www.google.com/url?q=https://www.nature.com/articles/ng0600_139&sa=D&source=editors&ust=1731543199836901&usg=AOvVaw3_14luEWyD-YIw8sFzSV02 |
Atoh1 | atonal bHLH transcription factor 1 | FlpO-ER | Random integration | Mouse | Wojcinski | Neural Development | 2019 | 30764875 | 6331265 | Contact Professor Joyner directly | joynera@mskcc.org | https://neuraldevelopment.biomedcentral.com/articles/10.1186/s13064-019-0128-y |
Bhlhe22 | basic helix-loop-helix family, member e22 | FlpO | START knock-in | Mouse | Cai | Developmental Biology | 2016 | 27151208 | 6369826 | Contact Professor Ross directly | saross@pitt.edu | https://linkinghub.elsevier.com/retrieve/pii/S0012160615301937 |
Cag | cytomegalovirus/chicken b-actin hybrid | FlpE-ER | Random Integration | Mouse | Hunter | Genesis | 2005 | 15729687 | 5432116 | No longer available or maintained | https://onlinelibrary.wiley.com/doi/epdf/10.1002/gene.20101 | |
Cag | cytomegalovirus/chicken b-actin hybrid | FlpE | Random integration | Mouse | Kanki | Experimental Animals | 2006 | 16651697 | RBRC | RBRC10707,RBRC10708 | https://www.jstage.jst.go.jp/article/expanim/55/2/55_2_137/_article/-char/ja/ | |
CamK2a | Calmodulin Kinase 2-alpha | FlpE | unknown | Mouse | Unpublished | Unpublished | Unpublished | 5440165 | Taconic - Not available | |||
Cdx2 | caudal type homeobox 2/neural-specific enhancer hybrid | FlpO | Random integration | Mouse | Abraira | Cell | 2017 | 28041852 | 5828010 | Jackson | 30288 | https://www.sciencedirect.com/science/article/pii/S0092867416316841 |
Cdx2 | caudal type homeobox 2 | FlpO | Random integration | Mouse | Britz | eLife | 2015 | 26465208 | 5911680 | Contact Professor Goulding directly | goulding@salk.edu | https://elifesciences.org/articles/04718 |
Crh | corticotropin releasing hormone | FlpO | IRES knock-in | Mouse | Unpublished | Unpublished | Unpublished | 6116854 | Jackson | 31559 | Unpublished | |
DbH | dopamine beta-hydroxylase | FlpO | START knock-in | Mouse | Robertson | Nature Neuroscience | 2013 | 23852112 | 5495939 | Jackson | 33952 | https://www.nature.com/articles/nn.3458 |
DbH | dopamine beta-hydroxylase | FlpO | START knock-in | Mouse | Sun | PLOS One | 2016 | 27441631 | 6118955 | MMRRC | 41577 | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0159474 |
DbH | dopamine beta-hydroxylase | FlpO | 2a knock-in | Mouse | Sun | PLOS One | 2016 | 27441631 | 5770774 | MMRRC | 41575 | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0159474 |
Dlx5/6 | Dlx5-Dlx6 intergenic enhancer/beta-globin promoter hybrid | Myc-FlpE | Random integration | Mouse | Miyoshi | Journal of Neuroscience | 2010 | 20130169 | 4421157 | Jackson | 10815 | http://www.jneurosci.org/content/30/5/1582.long |
EF1A | elongation factor 1-alpha | Flp | Random integration | Mouse | Takeuchi | Biochemical and Biophysical Research Communications | 2002 | 12051751 | RBRC | RBRC01251,RBRC01252 | https://www.sciencedirect.com/science/article/pii/S0006291X02003212 | |
Fezf2 | fez family zinc finger 2 | FlpO | 2a knock-in | Mouse | Matho | BioRxiv | 2020 | Contact Professor Huang directly | huangj@cshl.edu | https://www.biorxiv.org/content/10.1101/2020.04.22.054064v1 | ||
Gad2 | glutamate decarboxylase 2 | FlpO | IRES knock-in | Mouse | Alhadeff | Cell | 2018 | 29570993 | 6156370 | Contact Professor Hantman directly | hantamana@hhmi.org | https://www.cell.com/cell/fulltext/S0092-8674(18)30234-4 |
GFAP | glial fibrillary acidic protein | FlpO | Random integration | Mouse | Hara | Cancer Research | 2019 | 31315836 | 6294098 | Jackson | 33116 | https://cancerres.aacrjournals.org/content/79/15/3983.short?rss=1 |
Gsh2 | glutathione synthetase 2 | FlpE | IRES knock-in | Mouse | Unpublished | Unpublished | Unpublished | CARD | 2114 | http://cardb.cc.kumamoto-u.ac.jp/transgenic/strainsDetailAction.do?strainId=2107 | ||
Hcrt | hypocretin neuropeptide precursor | FlpO | 2a knock-in | Mouse | Chowdhury | eLife | 2019 | 31159922 | 6357834 | Contact Professor Yamanaka directly | yamank@riem.nagoy-u.ac.jp | https://elifesciences.org/articles/44927 |
Hoxb8 | homeobox B8 | FlpO | Random integration | Mouse | Zhang | The Journal of Clinical Investigation | 2018 | 29893745 | 6147797 | EMMA | 11094 | https://www.jci.org/articles/view/120913 |
Htr3a | 5-hydroxytryptamine receptor 3A | FlpO | IRES knock-in | Mouse | Schuman | Journal of Neuroscience | 2019 | 30413647 | Jackson | 30755 | https://www.jneurosci.org/content/39/1/125 | |
Lbx1 | ladybird homeobox 1 | FlpO | START knock-in | Mouse | Bourane | Science | 2015 | 26516282 | 5770780 | Contact Professor Goulding directly | goulding@salk.edu | https://science.sciencemag.org/content/350/6260/550 |
mGluR6 | glutamate metabotropic receptor 6 | FlpO | Random integration | Mouse | Unpublished | Unpublished | Unpublished | RBRC | RBRC09715 | Unpublished | ||
MMTV | mouse mammary tumor virus | FlpO | Random integration | Mouse | Lüönd | Journal of Mammary Gland Biology and Neoplasia | 2019 | 30209717 | Contact Professor Christofori directly | gerhard.christofori@unibas.ch | https://link.springer.com/article/10.1007/s10911-018-9412-4 | |
Mrgprb4 | MAS-related GPR, member B4 | EGFP-2a-FlpO | 2a knock-in; driver knock-out | Mouse | Vrontou | Nature | 2013 | 23364746 | 5448564 | Jackson | 21078 | https://www.nature.com/articles/nature11810 |
Nestin | nestin | FlpO-ER | Random integration | Mouse | Lao | Cell | 2012 | 22884371 | 5532191 | Contact Professor Joyner directly | joynera@mskcc.org | https://www.cell.com/cell-reports/fulltext/S2211-1247(12)00200-8 |
Nkx2.1 | NK2 homeobox 1 | FlpO | IRES knock-in | Mouse | He | Neuron | 2016 | 27618674 | 5700385 | Jackson | 28577 | https://www.sciencedirect.com/science/article/pii/S089662731630513X?via%3Dihub |
Nphs1 | nephrin | FlpO | Random integration | Mouse | Goldberg | Journal of the American Society of Nephrology | 2010 | 20150535 | 5431870 | Contact Professor Miner directly | minerj@wustl.edu | https://jasn.asnjournals.org/content/21/4/579 |
Npy | neuropeptide Y | FlpO | IRES knock-in | Mouse | Daigle | Cell | 2018 | 30007418 | 5903980 | Jackson | 30211 | https://www.sciencedirect.com/science/article/pii/S0092867418308031?via%3Dihub |
Pdx1 | pancreatic and duodenal homeobox 1 | FlpO | Random integration | Mouse | Schönhuber | Nature Medicine | 2014 | 25326799 | 5616872 | Contact Professor Saur directly | dieter.saur@tum.de | https://www.nature.com/articles/nm.3646 |
Pdx1 | pancreatic and duodenal homeobox 1 | FlpO | START knock-in | Mouse | Wu | PLOS One | 2017 | 28934293 | 6119579 | Contact Professor Ostrowski directly | ostrowsk@musc.edu | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0184984 |
Pet1 | FEV transcription factor, ETS family member | FlpE | Random Integration | Mouse | Jensen | Nature Neuroscience | 2008 | Contact Professor Dymecki directly | dymecki@genetics.med.harvard.edu | https://www.nature.com/articles/nn2050 | ||
Pgk1 | phosphoglycerate kinase 1 | Flpo | Random integration | Mouse | Wu Y | Plos One | 2009 | 19956655 | 4415609 | Jackson | 11065 | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008054 |
Phox2b | paired-like homeobox 2B | FlpO | BAC transgenic | Mouse | Hirsch | Genesis | 2013 | 23592597 | 5508639 | Jackson | 22407 | https://onlinelibrary.wiley.com/doi/abs/10.1002/dvg.22393 |
PlexinD1 | plexin D1 | FlpO | 2a knock-in | Mouse | Matho | BioRxiv | 2020 | Contact Professor Huang directly | huangj@cshl.edu | https://www.biorxiv.org/content/10.1101/2020.04.22.054064v1 | ||
Plxnd1 | plexin D1 | dgFlpO | IRES knock-in | Mouse | Daigle | Cell | 2018 | 30007418 | Contact Dr. Daigle | tanyad@alleninstitute.org | https://www.sciencedirect.com/science/article/pii/S0092867418308031?via%3Dihub | |
Pomc | Proopiomelanocortin | FlpE | Random Integration | Mouse | Vooijs | Oncogene | 1998 | 9671308 | 4353097 | No longer available or maintained | https://www.nature.com/articles/1202169 | |
Prkcd | protein kinase C delta | FlpO | 2a knock-in | Mouse | Unpublished | Unpublished | Unpublished | Contact Professor Li directly | bli@cshl.edu | Unpublished | ||
Pvalb | parvalbumin | FlpE | 2a knock-in | Mouse | Madisen | Neuron | 2015 | 25741722 | 5461313 | Jackson | 21191 | https://www.sciencedirect.com/science/article/pii/S0896627315001373 |
Pvalb | parvalbumin | FlpO | 2a knock-in | Mouse | Madisen | Neuron | 2015 | 25741722 | 5490601 | Jackson | 22730 | https://www.sciencedirect.com/science/article/pii/S0896627315001373 |
Pvalb | parvalbumin | FlpO | 2a knock-in | Rat | Unpublished | Unpublished | Unpublished | Contact Professor Berke directly | joshua.berke@ucsf.edu | https://www.biorxiv.org/content/10.1101/386474v2 | ||
Rasgrf2 | RAS protein-specific guanine nucleotide-releasing factor 2 | dgFlpO | 2a knock-in | Mouse | Daigle | Cell | 2018 | 30007418 | 5806617 | Jackson | 29589 | https://www.sciencedirect.com/science/article/pii/S0092867418308031?via%3Dihub |
Rorb | RAR related orphan receptor B | FlpO | IRES knock-in | Mouse | Daigle | Cell | 2018 | 30007418 | 5806628 | Jackson | 29590 | https://www.sciencedirect.com/science/article/pii/S0092867418308031?via%3Dihub |
Rorb | RAR related orphan receptor B | FlpO | 2a knock-in | Mouse | Daigle | Cell | 2018 | 30007418 | Contact Dr. Daigle | tanyad@alleninstitute.org | https://www.sciencedirect.com/science/article/pii/S0092867418308031?via%3Dihub | |
Slc17a6 | solute carrier family 17 member 6 (vesicular glutamate transporter) | FlpO | IRES knock-in | Mouse | Daigle | Cell | 2018 | 30007418 | 5903982 | Jackson | 30212 | https://www.sciencedirect.com/science/article/pii/S0092867418308031?via%3Dihub |
Slc32a1 | solute carrier family 32 member 1 (vesicluar gaba transporter) | FlpO | IRES knock-in | Mouse | Daigle | Cell | 2018 | 30007418 | 6150908 | Jackson | 31331 | https://www.sciencedirect.com/science/article/pii/S0092867418308031?via%3Dihub |
Slc32a1 | solute carrier family 32 member 1 (vesicluar gaba transporter) | FlpO | 2a knock-in | Mouse | Daigle | Cell | 2018 | 30007418 | 5806634 | Jackson | 29591 | https://www.sciencedirect.com/science/article/pii/S0092867418308031?via%3Dihub |
Slc6a3 | solute carrier family 6 member 3 (dopamine transporter) | FlpO | IRES knock-in | Mouse | Unpublished | Unpublished | Unpublished | 6316964 | Jackson | 33673 | Unpublished | |
Slc6a4 | solute carrier family 6 member 4 (serotonin transporter) | FlpO | IRES knock-in | Mouse | Unpublished | Unpublished | Unpublished | 6316965 | Jackson | 33674 | Unpublished | |
SST | somatostatin | FlpO | IRES knock-in | Mouse | He | Neuron | 2016 | 27618674 | 5700394 | Jackson | 28579 | https://www.sciencedirect.com/science/article/pii/S089662731630513X?via%3Dihub |
Tbr2 | eomesodermin (T-box brain protein 1) | FlpO-ER | 2a knock-in | Mouse | Matho | BioRxiv | 2020 | Contact Professor Huang directly | huangj@cshl.edu | https://www.biorxiv.org/content/10.1101/2020.04.22.054064v1 | ||
Tbx21 | T-box transcription factor 21 | FlpE-ER | IRES knock-in | Mouse | Gokmen | The Journal of Immunology | 2013 | 5575639 | Contact Professor Lord directly | Graham.lord@manchester.ac.uk | https://www.jimmunol.org/content/191/12/5925 | |
TH | tyrosine hydroxylase | FlpO | 2a knock-in | Mouse | Poulin | Nature Neuroscience | 2018 | 30104732 | MMRRC | 50618 | https://www.nature.com/articles/s41593-018-0203-4 | |
TH | tyrosine hydroxylase | FlpO | Random integration | Mouse | Imayoshi | Neuroscience Research | 2012 | 22343123 | 6324055 | RBRC | RBRC5168-RBRC5171 | https://www.sciencedirect.com/science/article/pii/S0168010212000247 |
Trf | transferrin | FlpE | Unknown | Mouse | Unpublished | Unpublished | Unpublished | 5440434 | Taconic - Not available | |||
Tshz1 | teashirt zinc finger homeobox 1 | FlpO | 2a knock-in | Mouse | Unpublished | Unpublished | Unpublished | Contact Professor Li directly | bli@cshl.edu | Unpublished | ||
VGlut2 | solute carrier family 17 member 6 (VGLUT2) | FlpO | IRES knock-in | Mouse | Alhadeff | Cell | 2018 | 29570993 | 6156365 | Contact Professor Hantman directly | hantmana@janelia.hhmi.org | https://www.cell.com/cell/fulltext/S0092-8674(18)30234-4 |
VIP | vasoactive intestinal protein | FlpO | IRES knock-in | Mouse | He | Neuron | 2016 | 27618674 | 5700390 | Jackson | 28578 | https://www.sciencedirect.com/science/article/pii/S089662731630513X?via%3Dihub |
Wnt1 | Wnt family member 1 | FlpE | Random Integration | Mouse | Awatramani | Nature Genetics | 2003 | 12923530 | 3774259 | Contact Professor Dymecki directly | dymecki@genetics.med.harvard.edu | https://www.nature.com/articles/ng1228 |
Wnt1 | Wnt family member 1 | Flp(F70L) | Random Integration | Mouse | Dymecki | Developmental Biology | 1998 | 9733573 | 3774259 | No longer available or maintained | https://www.sciencedirect.com/science/article/pii/S0012160698989710 | |
Wnt1 | Wnt family member 1 | FlpE-ER | Random Integration | Mouse | Hunter | Genesis | 2005 | 15729687 | 5432117 | No longer available or maintained | https://onlinelibrary.wiley.com/doi/epdf/10.1002/gene.20101 |